Bacilotetrin C analogue
Bacilotetrin C analogue is cytotoxic to triple-negative breast cancer cell line MDA-MB-231 with an IC50 of 0.48 μM. Bacilotetrin C analogue can induce tumor cell autophagy and has anti-tumor activity[1].
Product Specifications
UNSPSC
12352209
Target
Autophagy
Related Pathways
Autophagy
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O=C(CC[C@@H](C(N[C@@H](CCC(N1CCOCC1)=O)C2=O)=O)NC(C[C@H](OC([C@@H](NC([C@@H](CC(C)C)N2)=O)CC(C)C)=O)CCCCCCCCCCC)=O)N3CCOCC3
Molecular Formula
C44H76N6O10
Molecular Weight
849.11
References & Citations
[1]Auddy SS, et al: Discovery of Potent Anticancer Congeners Promoting Autophagy. ACS Med Chem Lett. 2024 Jul 25;15 (8) :1340-1350.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Curated Selection
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