Na+-Ca2+ Exchanger
Na+-Ca2+ Exchanger inhibitory peptide (XIP) is a Na+-Ca2+ exchanger inhibitor with a Ki of 200 nM. Na+-Ca2+ Exchanger inhibitory peptide inhibits the Na+-dependent Ca2+ uptake and the Na+-dependent Ca2+ efflux of sarcolemmal vesicles in a noncompetitive manner[1].
Product Specifications
Product Name Alternative
XIP
UNSPSC
12352209
Target
Na+/Ca2+ Exchanger
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Neurological Disease
Smiles
O=C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC2=CC=C(C=C2)O)C(N[C@@H](CCCCN)C(N[C@@H](CC3=CC=C(C=C3)O)C(N[C@@H](C(C)C)C(N[C@@H](CC4=CC=C(C=C4)O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC5=CC=C(C=C5)O)C(N[C@@H](CCC(O)=O)C(N[C@@H](C)C(NCC(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCC(O)=O)C(NCC(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCCNC(N)=N)N
Molecular Formula
C112H161N27O33
Molecular Weight
2413.64
References & Citations
[1]Z Li, et al. Identification of a peptide inhibitor of the cardiac sarcolemmal Na (+) -Ca2+ exchanger. J Biol Chem. 1991 Jan 15;266 (2) :1014-20.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Curated Selection
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