MP6 (TFA)
MP6 (Myr-FEEERA-OH) TFA is a myristoylated peptide. mP6 TFA inhibits the interaction of Gα13 with integrin β3 without disrupting talin-dependent integrin function. mP6 TFA can block the GTP usage of Rac1, Rap1, and Rab7, effectively inhibiting the infection of CHO-A24 cells[1].
Product Specifications
Product Name Alternative
Myr-FEEERA-OH (TFA)
UNSPSC
12352209
Target
Integrin
Related Pathways
Cytoskeleton
Field of Research
Infection
Purity
98.48
Smiles
O=C(O)C(F)(F)F.O=C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C)C(O)=O)=O)=O)=O)=O)[C@H](CC1=CC=CC=C1)NC(CCCCCCCCCCCCC)=O.[x]
Molecular Formula
C47H75N9O14.xC2HF3O2
Molecular Weight
990.15 (free base)
References & Citations
[1]Bondu V, et al. Low-affinity binding in cis to P2Y2R mediates force-dependent integrin activation during hantavirus infection. Mol Biol Cell. 2017 Oct 15;28 (21) :2887-2903.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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