Dalbinol

Dalbinol is a rotenoid compound. Dalbinol can inhibit Wnt/β-catenin signaling pathway and promote β-catenin degradation. Dalbinol inhibits tumor cells proliferation and induces apoptosis. Dalbinol has antitumor activity[1].

Product Specifications

CAS Number

[41993-79-7]

UNSPSC

12352005

Target

Apoptosis; Wnt; β-catenin

Related Pathways

Apoptosis; Stem Cell/Wnt

Field of Research

Cancer

Smiles

O[C@]12C3=CC(OC)=C(OC)C=C3OC[C@@]1([H])OC4=C(C[C@@H](O5)C(CO)=C)C5=CC=C4C2=O

Molecular Formula

C23H22O8

Molecular Weight

426.42

References & Citations

[1]Zhu X, et al. Dalbinol, a rotenoid from Amorpha fruticosa L., exerts anti-proliferative activity by facilitating β-catenin degradation in hepatocellular carcinoma cells. Oncotarget. 2017 Jul 18;8 (29) :47755-47766.