Aloesone

Aloesone is a phenolic compound. Aloesone can inhibit the production of ROS, the release of NO, M1 polarization, and apoptosis in RAW264.7 cells stimulated by LPS (HY-D1056) . Aloesone has anti-inflammatory and antioxidant activities[1][2].

Product Specifications

CAS Number

[40738-40-7]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Apoptosis; Reactive Oxygen Species (ROS)

Related Pathways

Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Purity

99.49

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1C=C(CC(C)=O)OC2=CC(O)=CC(C)=C12

Molecular Formula

C13H12O4

Molecular Weight

232.23

Precautions

H302, H315, H319, H335

References & Citations

[1]Reza Nazifi SM, et al. Antioxidant properties of Aloe vera components: a DFT theoretical evaluation. Free Radic Res. 2019 Aug;53 (8) :922-931.|[2]Wang Y, et al. Multiple Beneficial Effects of Aloesone from Aloe vera on LPS-Induced RAW264.7 Cells, Including the Inhibition of Oxidative Stress, Inflammation, M1 Polarization, and Apoptosis. Molecules. 2023 Feb 8;28 (4) :1617.