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Nidulalin A

Nidulalin A is a DNA topoisomerase II inhibitor with an IC50 of 2.2 μM. Nidulalin A has an IC50 of 172 μM for DNA topoisomerase I. Nidulalin A has certain cytotoxicity[1].

Product Specifications

CAS Number

[162901-86-2]

UNSPSC

12352005

Target

Topoisomerase

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Others

Smiles

COC([C@]12C(C(C3=C(O)C=C(C)C=C3O2)=O)=CC=C[C@H]1O)=O

Molecular Formula

C16H14O6

Molecular Weight

302.28

References & Citations

[1]Sato S, et al. Inhibition of DNA topoisomerases by nidulalin A derivatives. Biol Pharm Bull. 2000 Apr;23 (4) :511-2.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Curated Selection

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