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Buxbodine B

Buxbodine B is an inhibitor for acetylcholinesterase (AChE) with an IC50 of 50 μM. Buxbodine B can be used in research of Alzheimer's disease[1].

Product Specifications

CAS Number

[390362-51-3]

UNSPSC

12352211

Target

Cholinesterase (ChE)

Related Pathways

Neuronal Signaling

Field of Research

Neurological Disease

Smiles

C[C@]12[C@@]3([H])[C@@]4(CC[C@@]1([C@@]([C@H](C2)O)([H])[C@H](C)N(C)C)C)[C@@]5([C@@](C(C)(C(C=C5)=O)C)([H])CC3)C4

Molecular Formula

C26H41NO2

Molecular Weight

399.61

References & Citations

[1]Lam CW, et al., Bioactive steroidal alkaloids from Buxus macowanii Oliv. Steroids. 2015 Mar;95:73-9. |[2]Lam CW, et al., Bioactive steroidal alkaloids from Buxus macowanii Oliv. Steroids. 2015 Mar;95:73-9.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Isoform

AChE

Curated Selection

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