Clerodendrin (Standard)

Desvenlafaxine (Standard) is the analytical standard of Desvenlafaxine. This product is intended for research and analytical applications. Desvenlafaxine, the succinate salt form of the isolated major active metabolite of Venlafaxine (HY-B0196), is an orally active and BBB penetrated 5-HT and norepinephrine reuptake inhibitor, with IC50 values of 47.3 nM and 531.3 nM for hSERT and hNET, respectively. Desvenlafaxine shows weak binding affinity (62% inhibition at 100 μM) at the human dopamine (DA) transporter[1][2].

Product Specifications

CAS Number

[119738-57-7]

UNSPSC

12352005

Target

Interleukin Related; Reference Standards

Related Pathways

Immunology/Inflammation; Others

Field of Research

Inflammation/Immunology

Smiles

O=C1C2=C(O)C=C(O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)C(O)=O)O)O)O[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O)C(O)=O)C=C2OC(C5=CC=C(C=C5)O)=C1

Molecular Formula

C27H26O17

Molecular Weight

622.49

References & Citations

[1]Young KT, et, al. Inhibition of Interleukin-4 and β-Hexosaminidase Release in RBL-2H3 Cells by Compounds Isolated from Lobelia chinensis. 2021,27 (4) :251-6.