(-) -Securinine (nitrate)
(-) -Securinine (nitrate) is plant-derived alkaloid and also a GABAA receptor antagonist[1][2].
Product Specifications
CAS Number
[7104-26-9]
UNSPSC
12352005
Target
GABA Receptor
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Cancer; Neurological Disease
Smiles
O=C(O1)C=C2[C@@]13[C@](CCCC4)([H])N4[C@](C3)([H])C=C2.O[N+]([O-])=O
Molecular Formula
C13H16N2O5
Molecular Weight
280.28
References & Citations
[1]Stefanowicz-Hajduk J, et al. Securinine from Phyllanthus glaucus Induces Cell Cycle Arrest and Apoptosis in Human Cervical Cancer HeLa Cells. PLoS One. 2016 Oct 28;11 (10) :e0165372. |[2]Kalpana Gupta, et al. Securinine, a Myeloid Differentiation Agent with Therapeutic Potential for AML. PLoS One. 2011; 6 (6) : e21203.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
GTR15246435 1 Vial
Lentiviral mouse Tcstv3 shRNA (UAS) - Lentiviral mouse Tcstv3 shRNA (UAS, iRFP) (100)
Ask
View Details 
MBS6151853-01 0.1 mL
CLIC1 (Chloride Intracellular Channel Protein 1, Chloride Channel ABP, Nuclear Chloride Ion Channel 27, NCC27, Regulatory Nuclear Chloride Ion Channel Protein, hRNCC, G6, NCC27) (HRP)
Ask
View Details MBS6151853-02 5x 0.1 mL
CLIC1 (Chloride Intracellular Channel Protein 1, Chloride Channel ABP, Nuclear Chloride Ion Channel 27, NCC27, Regulatory Nuclear Chloride Ion Channel Protein, hRNCC, G6, NCC27) (HRP)
Ask
View Details ![Mouse Monoclonal BMP-6 Antibody (74219.11) [Alexa Fluor 488]](https://cdn.genprice.uk/genprice/uk/genprice5.webp)
NB120-10859AF488 0.1 mL
Mouse Monoclonal BMP-6 Antibody (74219.11) [Alexa Fluor 488]
Ask
View Details