Parvisoflavone B

Parvisoflavone B is a prenylated flavonoid. Parvisoflavone B can be isolated from root bark of Erythrina mildbraedii. Parvisoflavone B inhibits PTP1B activity with an IC50 of 42.6 μM. Parvisoflavone B inhibits α-glucosidase with an IC50 of 12.19 μM. Parvisoflavone B can be used in the research of type 2 diabetes and obesity[1][2].

Product Specifications

CAS Number

[50277-02-6]

UNSPSC

12352005

Target

Glycosidase; Phosphatase

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Metabolic Disease

Smiles

O=C1C(=COC2=CC=3OC(C=CC3C(O)=C12)(C)C)C=4C=CC(O)=CC4O

Molecular Formula

C20H16O6

Molecular Weight

352.34

References & Citations

[1]Jang J, et al. Prenylated flavonoids with PTP1B inhibitory activity from the root bark of Erythrina mildbraedii. Chem Pharm Bull (Tokyo) . 2008 Jan;56 (1) :85-8.|[2]Dendup T, et al. α-Glucosidase inhibitory activities of isoflavanones, isoflavones, and pterocarpans from Mucuna pruriens. Planta Med. 2014 May;80 (7) :604-8.