(Rac) -8-Gingerol
(Rac) -8-Gingerol is a non-volatile component. (Rac) -8-Gingerol can be extracted from ginger. (Rac) -8-Gingerol enhances Apoptosis. (Rac) -8-Gingerol decreases the level of phosphorylated EGFR and, accordingly, the phosphorylation levels of its downstream effectors, STAT3 and ERK. (Rac) -8-Gingerol exhibits anticancer activity against colorectal cancer[1].
Product Specifications
CAS Number
[77398-92-6]
UNSPSC
12352005
Target
Apoptosis; EGFR; PERK; STAT
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Smiles
O=C(CC(CCCCCCC)O)CCC1=CC=C(C(OC)=C1)O
Molecular Formula
C19H30O4
Molecular Weight
322.44
References & Citations
[1]Hu SM, et al. 8 Gingerol regulates colorectal cancer cell proliferation and migration through the EGFR/STAT/ERK pathway. Int J Oncol. 2020 Jan;56 (1) :390-397.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
STAT3
Curated Selection
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