Stigmalactam
Stigmalactam is an aristolactam-type alkaloid extracted from Orophea enterocarpa with anticancer effects. Stigmalactam induces apoptosis via the mitochondrial pathway, with the activation of caspase-3/9, and a decrease in mitochondrial membrane potential (MTP) . Stigmalactam exhibits antioxidant activity by decreasing ROS production. Stigmalactam can be used for liver and breast cancer research[1].
Product Specifications
CAS Number
[289499-72-5]
UNSPSC
12352005
Target
Apoptosis; Caspase; Mitochondrial Metabolism; Reactive Oxygen Species (ROS)
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Field of Research
Cancer
Smiles
O=C1NC2=CC3=CC=C(C=C3C4=C2C1=C(OC)C(OC)=C4OC)O
Molecular Formula
C18H15NO5
Molecular Weight
325.32
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
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