Xanthoascin

Xanthoascin (Compound 1) is a natural phenolic metabolite with strong anti plant pathogen activity. Xanthoascin can be extracted from the solid fermentation product of endophytic fungus Aspergillus sp. IFB-YXS isolated from Ginkgo biloba leaves. Xanthoascin has a MIC of 0.3125 µg/mL against Clavibacter michiganense subsp. Sepedonicus and moderate inhibitory activity against other pathogens (MIC = 5-20 µg/mL) . Xanthoascin can disrupt the permeability of bacterial cell membranes, leading to nucleic acid leakage[1].

Product Specifications

CAS Number

[61391-08-0]

UNSPSC

12352005

Target

Bacterial

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Smiles

[C-]#[N+]C(/C([N+]#[C-])=C/C1=CC=C2OC(C)(CCC2=C1)C)=C\C3=CC=C(C=C3)O

Molecular Formula

C23H20N2O2

Molecular Weight

356.42

References & Citations

[1]Zhang W, et al. Natural phenolic metabolites from endophytic Aspergillus sp. IFB-YXS with antimicrobial activity. Bioorg Med Chem Lett. 2015 Jul 1;25 (13) :2698-701.