Phenicin
Phenicin (Phoenicine), a microbial metabolite, is an irreversible HMG-CoA reductase (HMGCR) inhibitor. Phenicin can be isolated from cultures of Penicillium phoeniceum and Penicillium rubrum. Phenicin specifically inhibits the conversion of HMG-CoA to mevalonate catalyzed by HMGCR, effectively inhibiting cholesterol synthesis[1].
Product Specifications
CAS Number
[128-68-7]
Product Name Alternative
Phoenicine
UNSPSC
12352211
Target
HMG-CoA Reductase (HMGCR)
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Others
Smiles
O=C1C=C(C)C(C(O)=C1C(C(C=C2C)=O)=C(O)C2=O)=O
Molecular Formula
C14H10O6
Molecular Weight
274.23
References & Citations
[1]Hasumi K, et al. Irreversible inhibition of 3-hydroxy-3-methylglutaryl coenzyme A reductase by phenicin (phoenicine) . J Antibiot (Tokyo) . 1987 Feb;40 (2) :224-6.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
