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Panowamycin B

Panowamycin B is an isochroman compound that can be produced by Streptomyces sp. K07-0010. Panowamycin B exhibits antitrypanosomal activity against the Trypanosoma brucei brucei GUTat 3.1 strain (IC50: 3.30 μg/mL) . Panowamycin B shows weak cytotoxicity towards human fetal lung fibroblast MRC-5 cells (IC50: 13 μg/mL) . Panowamycin B can be used for research in the field of antitrypanosomal studies[1].

Product Specifications

CAS Number

[1375224-56-8]

UNSPSC

12352005

Target

Parasite

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

OCC[C@@H]1C2=CC(C)=CC=C2[C@@H]([C@](O1)([H])[C@H](C)[C@@H](O)C)C

Molecular Formula

C17H26O3

Molecular Weight

278.39

References & Citations

[1]Hashida J, et al. Panowamycins A and B, new antitrypanosomal isochromans produced by Streptomyces sp. K07-0010. J Antibiot (Tokyo) . 2012 Apr;65 (4) :197-202.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Curated Selection

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