Berkeleyamide B
Berkeleyamide B is a dual matrix metalloproteinase-3 (MMP-3) and caspase-1 inhibitor. Berkeleyamide B is promising for research of cancers and inflammatory disease (e.g., rheumatoid arthritis) [1].
Product Specifications
CAS Number
[1019854-22-8]
UNSPSC
12352005
Target
Caspase; MMP
Related Pathways
Apoptosis; Metabolic Enzyme/Protease
Field of Research
Cancer; Inflammation/Immunology
Smiles
CC(OC(C1=CC=CC=C1)C2=CC(C(C(NC(CC(C)C)=O)=O)=CO2)=O)=O
Molecular Formula
C20H21NO6
Molecular Weight
371.38
References & Citations
[1]Stierle AA, et al. The berkeleyamides, amides from the acid lake fungus Penicillum rubrum. J Nat Prod. 2008 May;71 (5) :856-60.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Caspase 1; MMP-3
Curated Selection
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