Mazethramycin B
Mazethramycin B (Compound II) is an antitumor antibiotic. Mazethramycin B can be isolated from the Streptomyces thioluteusM ME561-L4. Mazethramycin B has a broad-spectrum antimicrobial activity (such as MICs of 1.56 and 6.25 μg/mL for the bacteria Bacillus subtilis PCI 219 and the fungus Candida pseudotropicalis, resepectively) . Mazethramycin B significantly increases survival in L1210 leukemia mice model[1].
Product Specifications
CAS Number
[68373-95-5]
UNSPSC
12352005
Target
Antibiotic; Bacterial; Fungal
Related Pathways
Anti-infection
Field of Research
Cancer; Infection
Smiles
O=C(NC)/C=C/C1=CN2C(C3=CC=C(C)C(O)=C3NC(C2C1)OC)=O
Molecular Formula
C18H21N3O4
Molecular Weight
343.38
References & Citations
[1]Kunimoto S, et al. Mazethramycin, a new member of anthramycin group antibiotics. J Antibiot (Tokyo) . 1980 Jun;33 (6) :665-7.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
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