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Lyso-laurdan

Lyso-laurdan, a derivative of Laurdan (HY-D0080), is a fluorescent probe. Lyso-Laurdan accumulates in the lysosome via a morpholine group that is entrapped in lysosome via protonation to its cationic form in the acidic compartment. Lyso-laurdan is localized to lysosomes, allowing for the study of lysosomal membranes[1].

Product Specifications

CAS Number

[3091879-73-8]

UNSPSC

12352005

Target

Fluorescent Dye

Related Pathways

Others

Field of Research

Others

Smiles

O=C(CN(C)C1=CC2=CC=C(C(CCCCCCCCCCC)=O)C=C2C=C1)NCCCN3CCOCC3

Molecular Formula

C32H49N3O3

Molecular Weight

523.75

References & Citations

[1]Wong AM, et al. Organelle-targeted Laurdans measure heterogeneity in subcellular membranes and their responses to saturated lipid stress. bioRxiv [Preprint]. 2024 Apr 20:2024.04.16.589828. doi: 10.1101/2024.04.16.589828. Update in: ACS Chem Biol. 2024 Aug 16;19 (8) :1773-1785.

Shipping Conditions

Room temperature

Scientific Category

Dye Reagents

Clinical Information

No Development Reported

Curated Selection

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