2-O-Methylatromentin

2-O-Methylatromentin is an anti-neuroinflammatory agent. 2-O-Methylatromentin shows inhibitory activity on the production of pro-inflammatory cytokines TNF-α, IL-6 and IL-1β in Lipopolysaccharides (HY-D1056) (LPS) -induced BV-2 microglial cells. 2-O-Methylatromentin can be used for the study of neuroinflammatory related diseases[1].

Product Specifications

CAS Number

[121254-55-5]

UNSPSC

12352005

Target

Interleukin Related; TNF Receptor

Related Pathways

Apoptosis; Immunology/Inflammation

Field of Research

Inflammation/Immunology; Neurological Disease

Smiles

OC1=CC=C(C2=C(O)C(C(C3=CC=C(O)C=C3)=C(OC)C2=O)=O)C=C1

Molecular Formula

C19H14O6

Molecular Weight

338.31

References & Citations

[1]Zhang H, et al. Novel p-terphenyls with anti-neuroinflammatory activity from fruiting bodies of the Chinese edible mushroom Thelephora ganbajun Zang. Bioorg Chem. 2025 Jun 1;159:108414.