Crocatin B

Crocatin B is found in P. crocatum Ruiz & Pav. Crocatin B exerts anti-inflammatory activity by inhibiting the expression of TNF-α and ICAM-1. Crocatin B has anti-tumor activity[1][2].

Product Specifications

CAS Number

[143816-02-8]

UNSPSC

12352211

Target

Integrin; TNF Receptor

Related Pathways

Apoptosis; Cytoskeleton

Field of Research

Cancer; Inflammation/Immunology

Smiles

C[C@@H]([C@@]([C@H]1O)(C=C(C2=O)OC)CC=C)[C@@H](C3=CC(OC)=C(OC)C(OC)=C3)[C@]12OC

Molecular Formula

C23H30O7

Molecular Weight

418.48

References & Citations

[1]Meiridha MA, et al. Cytotoxic Activities of Extracts and Isolated Compounds of Some Potential Sumatran Medicinal Plants against MCF-7 and HSC-3 Cell Lines. J. Math. Fund. Sci., Vol. 51, No. 3, 2019, 225-242.|[2]Nilda L, et al. Anti-Inflammatory Effect of Isolate Compounds from Ethyl Acetate Fraction of Piper crocatum Ruiz and Pav Leaves on Lipopolysaccharide-induced RAW 264.7 Cells. HAYATI J Biosci Vol. 30 No. 1, January 2023.