Deoxytopsentin

Deoxytopsentin is a compound that can be found in marine sponges. It is an inhibitor of pyruvate kinase (PK) in methicillin-resistant Staphylococcus aureus (MRSA), with an IC50 value of 240 nM. Deoxytopsentin can be used in research in the field of anti-infection [1].

Product Specifications

CAS Number

[112515-42-1]

UNSPSC

12352005

Target

Pyruvate Kinase

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Infection

Smiles

O=C(C1=CNC2=C1C=CC=C2)C3=NC=C(C4=CNC5=C4C=CC=C5)N3

Molecular Formula

C20H14N4O

Molecular Weight

326.35

References & Citations

[1]Veale CG, et al. Synthetic analogues of the marine bisindole deoxytopsentin: potent selective inhibitors of MRSA pyruvate kinase. J Nat Prod. 2015 Mar 27;78 (3) :355-62.