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Acutumidine

Acutumidine (compound 4) is an alkaloid with anti-HBV activity that can be isolated from Hypserpa nitida Miers. Acutumidine inhibits the production of HBsAg in Hep G2.2.15 cells stably transfected with HBV genome with an IC50 value of 2.023 mM[1].

Product Specifications

CAS Number

[18145-26-1]

UNSPSC

12352005

Target

HBV

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

COC([C@@]12[C@](C3)(CCN2)[C@]4([C@@H](C(OC)=CC4=O)O)[C@H](C1)Cl)=C(OC)C3=O

Molecular Formula

C18H22ClNO6

Molecular Weight

383.82

References & Citations

[1]Pi Cheng, et al. Two new alkaloids and active anti-hepatitis B virus constituents from Hypserpa nitida. Bioorganic & medicinal chemistry letters 17.19 (2007) : 5316-5320.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Curated Selection

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