Glaucarubin

Glaucarubin is a bitter lactone found in Simaruba glauca. Glaucarubin can be used as an amœbicide for amebiasis research. Glaucarubin is well tolerated, with LD50s of 1,600 mg/kg for mice and 6,400 mg/kg for rats[1][2].

Product Specifications

CAS Number

[1448-23-3]

UNSPSC

12352211

Target

Parasite

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

C[C@@]12[C@]3([H])[C@]45[C@@]([C@H]([C@H]([C@@]3(OC5)O)O)C)([H])[C@H](C(O[C@]4([H])C[C@@]1([H])C(C)=C[C@@H]([C@H]2O)O)=O)OC([C@@](C)(O)CC)=O

Molecular Formula

C25H36O10

Molecular Weight

496.55

References & Citations

[1]KARTHA G, et al. CRYSTAL AND MOLECULAR STRUCTURE OF GLAUCARUBIN. Nature. 1964 Apr 25;202:389-90.|[2]DEL POZO EC, et al. Clinical trial of glaucarubin in treatment of amebiasis. Am J Med. 1956 Mar;20 (3) :412-7.