Polymyxin A2

Polymyxin A2 is a heteropeptide antibiotic found in different strains of Bacillus polymyxa, and its effect against Gram-negative bacteria is greater than that against Gram-positive bacteria[1].

Product Specifications

CAS Number

[65454-51-5]

UNSPSC

12352211

Target

Antibiotic; Bacterial

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

CC(CCCCC(N[C@H](C(N[C@H](C(N[C@@H](C(N[C@H](C(N[C@H]1CCN)=O)CCNC([C@@H](NC([C@@H](NC([C@H](CCN)NC([C@H]([C@H](O)C)NC([C@H](NC1=O)CC(C)C)=O)=O)=O)CCN)=O)[C@H](C)O)=O)=O)CCN)=O)[C@H](C)O)=O)CCN)=O)C

Molecular Formula

C50H94N16O14

Molecular Weight

1143.38

References & Citations

[1]Sandra Mikhail, et al. Evaluation of the Synergy of Ceftazidime-Avibactam in Combination with Meropenem, Amikacin, Aztreonam, Colistin, or Fosfomycin against Well-Characterized Multidrug-Resistant Klebsiella pneumoniae and Pseudomonas aeruginosa. Antimicrob Agents Chemother. 2019 Jul 25;63 (8) :e00779-19.