Adxanthromycin A

Adxanthromycin A, a microbial metabolite, is a ICAM-1/LFA-1 mediated cell adhesion inhibitor[1].

Product Specifications

CAS Number

[223740-97-4]

UNSPSC

12352005

Target

Integrin

Related Pathways

Cytoskeleton

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

C[C@@]1(C2=CC(O)=C(C(O)=O)C(C)=C2C(C3=C(O)C(C)=CC=C31)=O)OO[C@]4(C5=CC(O[C@H]6O[C@@H]([C@@H]([C@@H]([C@H]6O)O)O)CO)=C(C(O)=O)C(C)=C5C(C7=C(O)C(C)=CC=C74)=O)C

Molecular Formula

C42H40O17

Molecular Weight

816.76

References & Citations

[1]Takahashi S, et al. Adxanthromycins A and B, new inhibitors of ICAM-1/LFA-1 mediated cell adhesion molecule from Streptomyces sp. NA-148. II. Physico-chemical properties and structure elucidation. J Antibiot (Tokyo) . 2000 Feb;53 (2) :163-70.