Collismycin B
Collismycin B is a potent Dexamethasone (HY-14648) -glucocorticoid receptor inhibitor with an IC50 value of 10 µM. Collismycin B shows antimicrobial activity. Collismycin B shows cytotoxicity[1].
Product Specifications
CAS Number
[158792-25-7]
UNSPSC
12352005
Target
Bacterial; Glucocorticoid Receptor
Related Pathways
Anti-infection; Immunology/Inflammation; Vitamin D Related/Nuclear Receptor
Field of Research
Cancer; Infection
Smiles
O/N=C\C1=NC(C2=CC=CC=N2)=CC(OC)=C1SC
Molecular Formula
C13H13N3O2S
Molecular Weight
275.33
References & Citations
[1]Shindo K, et al. Collismycins A and B, novel non-steroidal inhibitors of dexamethasone-glucocorticoid receptor binding. J Antibiot (Tokyo) . 1994 Sep;47 (9) :1072-4.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Curated Selection
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