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Phenazostatin B

Phenazostatin B is a phenazine Substance that has the protective effect of new neuron cells. Phenazostatin B can scavenge free radicals, protect N18-RE 105 nerve cells from glutamate toxicity, and inhibit lipid peroxidation. Phenazostatin B inhibits glutamate toxicity in N18-RE-105 cells with an EC50 of 0.33 μg/mL[1].

Product Specifications

CAS Number

[73649-05-5]

UNSPSC

12352005

Target

Others

Related Pathways

Others

Field of Research

Neurological Disease

Smiles

C[C@@H](C1=CC=CC2=C1N=C(C=CC=C3C(OC)=O)C3=N2)[C@H](C4=CC=CC5=C4N=C(C=CC=C6C(OC)=O)C6=N5)C

Molecular Formula

C32H26N4O4

Molecular Weight

530.57

References & Citations

[1]W G Kim, et al. New diphenazines with neuronal cell protecting activity, phenazostatins A and B, produced by Streptomyces sp. J Antibiot (Tokyo) . 1997 Sep;50 (9) :715-21.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Curated Selection

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