Eponemycin
Eponemycin is an antibiotic that exhibits antitumor activity. Eponemycin exhibits cytotoxicity in cancer cells B16-F10, L1210, P388 and HCT-116 with IC50 of 0.0017, 0.01, 0.031 and 0.0097 µg/mL, respectively. Eponemycin inhibits the DNA synthesis in B16-F10 and Mitomycin C with IC50 of 0.1 µg/mL and 0.41 µg/mL[1].
Product Specifications
CAS Number
[126509-46-4]
UNSPSC
12352005
Target
Antibiotic; DNA/RNA Synthesis
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Field of Research
Cancer; Infection
Smiles
CC(C)CCCCC(N[C@@H](CO)C(N[C@@H](CC(C)=C)C([C@]1(CO1)CO)=O)=O)=O
Molecular Formula
C20H34N2O6
Molecular Weight
398.49
References & Citations
[1]Sugawara K, et al., Eponemycin, a new antibiotic active against B16 melanoma. I. Production, isolation, structure and biological activity. J Antibiot (Tokyo) . 1990 Jan;43 (1) :8-18.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Curated Selection
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