Cyclothialidine B
Cyclothialidine B inhibits escherichia coli DNA helicases with an IC50 of 0.7 μM[1].
Product Specifications
CAS Number
[194276-76-1]
UNSPSC
12352005
Target
DNA/RNA Synthesis
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Infection
Smiles
O=C(N[C@@H](CSCC1=C(O)C=C(O)C=C1C(OC2)=O)C(N[C@@H](C)C(O)=O)=O)[C@H]2NC([C@H]3N(CC[C@H]3O)C([C@@H](N)C)=O)=O
Molecular Formula
C25H33N5O11S
Molecular Weight
611.62
References & Citations
[1]N Nakada, et al. Characterization of the binding site for cyclothialidine on the B subunit of DNA gyrase. J Biol Chem. 1995 Jun 16;270 (24) :14286-91.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Curated Selection
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