Chlovalicin

Chlovalicin is found in the strain of Sporothrix sp. FO-4649. In the presence of 0.2 U/mL IL-6, Chlovalicin inhibits the growth of L6-dependent MH60 cells with lC50 of 7.5 μM. Chlovalicin also inhibits the growth of B16 melanoma cells with lC50 of 38 μM. Chlovalicin also displays inhibitory activity on osteoclastogenesis[1].

Product Specifications

CAS Number

[179799-38-3]

UNSPSC

12352211

Target

Others

Related Pathways

Others

Field of Research

Cancer

Smiles

O[C@@]1([C@@]2([C@H](O2)C/C=C(C)\C)C)[C@](O)(CCC([C@H]1OC)=O)CCl

Molecular Formula

C16H25ClO5

Molecular Weight

332.82

References & Citations

[1]Marte Jenssen, et al. Chlovalicin B, a Chlorinated Sesquiterpene Isolated from the Marine Mushroom Digitatispora marina. Molecules. 2021 Dec 13;26 (24) :7560.