Dihydrohonokiol B

Dihydrohonokiol B (Dihydrohonokiol) is an anxiolytic agent. Dihydrohonokiol B can reduce the neurotoxicity induced by amyloid β protein by stimulating the GABAC receptor. Dihydrohonokiol B can be used in the research of neurodegenerative diseases such as Alzheimer's disease[1][2].

Product Specifications

CAS Number

[219565-74-9]

Product Name Alternative

Dihydrohonokiol

UNSPSC

12352005

Target

GABA Receptor

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Field of Research

Neurological Disease

Purity

99.29

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

OC1=CC=C(CCC)C=C1C2=CC(CC=C)=C(O)C=C2

Molecular Formula

C18H20O2

Molecular Weight

268.35

References & Citations

[1]Esumi T, et al. Efficient synthesis and structure-activity relationship of honokiol, a neurotrophic biphenyl-type neolignan. Bioorg Med Chem Lett. 2004 May 17;14 (10) :2621-5.|[2]Liu B, et al. Anxiolytic agent, dihydrohonokiol-B, recovers amyloid beta protein-induced neurotoxicity in cultured rat hippocampal neurons. Neurosci Lett. 2005 Aug 12-19;384 (1-2) :44-7.