Bequinostatin A

Bequinostatin A is a benzo[a]naphthacenequinone metabolite that can be isolated from Streptomyces sp. MI384-DF12. Bequinostatin A shows considerable inhibitory activity against human pi class glutathione S-transferase (GST pi) [1].

Product Specifications

CAS Number

[151013-37-5]

UNSPSC

12352005

Target

Glutathione S-transferase

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Inflammation/Immunology

Smiles

OC1=C2C3=CC(C(C4=CC(O)=CC(O)=C4C5=O)=O)=C5C(O)=C3C(CC2=CC(CCCCC)=C1C(O)=O)O

Molecular Formula

C28H24O9

Molecular Weight

504.48

References & Citations

[1]Aoyama T, et al. Bequinostatins A and B new inhibitors of glutathione S-transferase, produced by Streptomyces sp. MI384-DF12. Production, isolation, structure determination and biological activities. J Antibiot (Tokyo) . 1993 Jun;46 (6) :914-20.