Sudachitin
Sudachitin, a polymethoxyflavone that can be isolated from Citrus sudachi, suppresses lipopolysaccharide-induced inflammatory responses in mouse macrophage-like RAW264 cells. Sudachitin can activate the p38MAPK pathway and inhibit the ERK1/2 pathway in HaCaT cells[1].
Product Specifications
CAS Number
[4281-28-1]
UNSPSC
12352005
Target
ERK; p38 MAPK
Related Pathways
MAPK/ERK Pathway; Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Smiles
O=C1C=C(C2=CC(OC)=C(O)C=C2)OC3=C1C(O)=C(OC)C(O)=C3OC
Molecular Formula
C18H16O8
Molecular Weight
360.31
References & Citations
[1]Keizo Yuasa, et al. Sudachitin, a polymethoxyflavone from Citrus sudachi, suppresses lipopolysaccharide-induced inflammatory responses in mouse macrophage-like RAW264 cells. Biosci Biotechnol Biochem. 2012;76 (3) :598-600.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
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