TP-1161

TP-1161 is a novel thiopeptide antibiotic. TP-1161 has strong inhibitory effects on various Gram positive bacteria (MIC = 0.25-4 μg/mL), but is inactive against Gram negative bacteria. TP-1161 can be used for research on bacterial infections[1].

Product Specifications

CAS Number

[1287303-66-5]

UNSPSC

12352005

Target

Antibiotic; Bacterial

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

CC(CNC(C(NC(C(NC(C1=CC=C(C2=NC(C(N[C@@](C(N/C(C3=NC(C(NCC4=NC(C(N[C@H](C5=NC(C(NC(C(NC(C6=NC7=CO6)=C)=O)=C)=O)=CS5)C)=O)=CS4)=O)=C(O3)C)=C/C)=O)([H])[C@H](O)C)=O)=CS2)C7=N1)=O)=C)=O)=C)=O)=O

Molecular Formula

C50H47N15O13S3

Molecular Weight

1162.20

References & Citations

[1]Engelhardt K, et al. Production of a new thiopeptide antibiotic, TP-1161, by a marine Nocardiopsis species. Appl Environ Microbiol. 2010 Aug;76 (15) :4969-76.