TIE2 Y1108F Recombinant Human Active Protein Kinase
TIE2 plays an important role in vascular formation and maintenance. Mutations in TIE2 lead to vascular malformations, which are painful vascular lesions that cause disfigurement, bleeding, and thrombosis. TIE2 Y1108F is the most mutation of TIE2. TIE2 Y1108F Recombinant Human Active Protein Kinase is a recombinant TIE2 Y1108F protein that can be used to study TIE2 Y1108F-related functions[1].
Product Specifications
UNSPSC
12352211
Target
Tie
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Cardiovascular Disease
Smiles
[TIE2Y1108FRecombinantHumanActiveProteinKinase]
References & Citations
[1]Kennedy MA, et al. A Tie2 kinase mutation causing venous malformations increases phosphorylation rates and enhances cooperativity. Biochem Biophys Res Commun. 2019 Feb 19;509 (4) :898-902.
Shipping Conditions
Room temperature
Scientific Category
Enzyme
Clinical Information
No Development Reported
Curated Selection
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