BIN-3

BIN-3 is a novel near-infrared fluorescent probe. BIN-3 has excellent biocompatibility, no cytotoxicity, and no hemolysis. BIN-3 can be used for highly sensitive and selective imaging of drug-resistant bacterial infections expressing β-lactam enzymes in live mice[1].

Product Specifications

CAS Number

[3086791-47-8]

UNSPSC

12352005

Target

Bacterial; Fluorescent Dye

Related Pathways

Anti-infection; Others

Field of Research

Infection

Smiles

CCC[N+]1=C(C(C)(C2=CC=CC=C21)C)/C=C/C3=C4OC5=C(C=C4CCC3)C=C(C(OCC6=C(N7C([C@H]([C@H]7SC6)NC(CCC8=CN(N=N8)CC[N+](C)(CCCS(=O)([O-])=O)C)=O)=O)C(O)=O)=C5)COC(NCC)=O.[I-]

Molecular Formula

C52H65IN8O11S2

Molecular Weight

1169.15

References & Citations

[1]Chen F, et al. Highly Sensitive In Vivo Imaging of Bacterial Infections with a Hydrophilicity-Switching, Self-Immobilizing, Near-Infrared Fluorogenic β-Lactamase Probe Enriched within Bacteria. Adv Sci (Weinh) . 2025 Feb;12 (5) :e2408559.