Golgi-P

Golgi-P is a near-infrared Golgi-targeted fluorescent probe specifically used for the detection of Golgi polarity in living cells and living tissues. Golgi-P exhibits a significant polarity-dependent spectral behavior, with its emission wavelength shifting redward with polarity (Ex/Em: 700 nm/780-825 nm) . Golgi-P achieves near-infrared fluorescence imaging directly in the brain tissue of depressed mice. Golgi-P combines polarity sensing with Golgi-targeting functionality, providing a new tool for the molecular diagnosis of depression[1].

Product Specifications

UNSPSC

12352005

Target

Fluorescent Dye

Related Pathways

Others

Field of Research

Neurological Disease

Smiles

CC1(C)C(C=CC=C2)=C2N(CCC(C[C@@](C(O)=O)([H])CS)=O)/C1=C/C=C3CCCC(/C=C/C4=[O+][B-](F)(OC(C5=CC=CC=C5)=C4)F)=C\3Cl

Molecular Formula

C36H37BClF2NO5S

Molecular Weight

680.01

References & Citations

[1]Li P, et al. Golgi Apparatus Polarity Indicates Depression-Like Behaviors of Mice Using in Vivo Fluorescence Imaging. Anal Chem. 2019 Mar 5;91 (5) :3382-3388.