BG-Tetrazine

BG-Tetrazine (BG-Tz; SNAP-Tetrazine) is a SNAP tag substrate that contains a methyl tetrazine group. BG-Tetrazine can specifically covalently label the target protein of the intracellular SNAP-tag fusion. The tetrazine group it carries can rapidly and efficiently undergo a bioorthogonal reaction with functional groups such as trans cyclooctene (TCO), thereby enabling multiple labeling, functionalization or enrichment of proteins. BG-Tetrazine can be applied in click chemistry[1].

Product Specifications

Product Name Alternative

BG-Tz; SNAP-Tetrazine

UNSPSC

12352005

Target

Biochemical Assay Reagents

Related Pathways

Others

Field of Research

Others

Smiles

CC1=NN=C(N=N1)C2=CC=C(C=C2)CC(NCC3=CC=C(C=C3)COC4=NC(N)=NC5=C4N=CN5)=O

Molecular Formula

C24H22N10O2

Molecular Weight

482.50

References & Citations

[1]Wilhelm J, et al. Kinetic and Structural Characterization of the Self-Labeling Protein Tags HaloTag7, SNAP-tag, and CLIP-tag. Biochemistry. 2021 Aug 24;60 (33) :2560-2575.