Methantheline (bromide)

Methantheline bromide is a quaternary Ammonium derivate with anticholinergic activity. Methantheline bromide results in a significant greater reduction of axillary sweat production. Methyl bromide can be used in the research of intractable peptic ulcers[1][2].

Product Specifications

CAS Number

[53-46-3]

UNSPSC

12352005

Hazard Statement

H302-H332

Target

Drug Derivative; mAChR

Related Pathways

GPCR/G Protein; Neuronal Signaling; Others

Field of Research

Metabolic Disease; Inflammation/Immunology

Smiles

O=C(OCC[N+](CC)(CC)C)C1C2=C(OC3=C1C=CC=C3)C=CC=C2.[Br-]

Molecular Formula

C21H26BrNO3

Molecular Weight

420.34

Precautions

P261-P264-P270-P271-P304+P340-P330-P501

References & Citations

[1]LIEBOWITZ D, et al. Treatment of intractable peptic ulcer with methantheline (banthine) bromide. J Am Med Assoc. 1952 Oct 18;150 (7) :672-8. English, Undetermined Language. |[2]Müller C, et al. Efficacy and safety of methantheline bromide (Vagantin (®) ) in axillary and palmar hyperhidrosis: results from a multicenter, randomized, placebo-controlled trial. J Eur Acad Dermatol Venereol. 2013 Oct;27 (10) :1278-84.