D-Sorbitol, M400 (GMP Like)
D-Sorbitol, M400 (GMP Like) is the GMP Like class D-Sorbitol, M400 that can be used as pharmaceutical excipients. D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and dietary supplement[1].
Product Specifications
CAS Number
[50-70-4]
UNSPSC
12352211
Target
Endogenous Metabolite
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Smiles
OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CO
Molecular Formula
C6H14O6
Molecular Weight
182.17
References & Citations
[1]Tan, K., et al., The mannitol operon repressor MtlR belongs to a new class of transcription regulators in bacteria. J Biol Chem, 2009. 284 (52) : p. 36670-9. |[2]Nishiyama, A., et al., Mannitol lowers fat digestibility and body fat accumulation in both normal and cecectomized rats. J Nutr Sci Vitaminol (Tokyo), 2009. 55 (3) : p. 242-51.|[3]Hanieh, H. and E. Sakaguchi, Effect of D-mannitol on feed digestion and cecotrophic system in rabbits. Anim Sci J, 2009. 80 (2) : p. 157-62.|[4]Kaufmann AM, et al. Aggravation of vasogenic cerebral edema by multiple-dose mannitol. J Neurosurg. 1992;77 (4) :584-589. |[5]Xiao J, et al. Sakaguchi E. Mannitol improves absorption and retention of calcium and magnesium in growing rats. Nutrition. 2013;29 (1) :325-331.|[6]Paczynski RP, et al. Multiple-dose mannitol reduces brain water content in a rat model of cortical infarction. Stroke. 1997;28 (7) :1437-1444.|[7]Jeon HJ, et al. D-Mannitol Induces a Brown Fat-like Phenotype via a β3-Adrenergic Receptor-Dependent Mechanism. Cells. 2021;10 (4) :768. Published 2021 Mar 31.
Shipping Conditions
Room temperature
Scientific Category
GMP Small Molecules
Clinical Information
No Development Reported
Curated Selection
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