Epi-D-Captopril
Epi-D-Captopril (epi-D-SQ 14225) is a stereoisomer of Captopril (HY-B0368) and an inhibitor of metallo-β-lactamases (MBLs) . The IC50 values of epi-D-Captopril against NDM-1, IMP-1, and VIM-2 are 64 μM, 173 μM, and 5.5 μM, respectively. epi-D-Captopril is expected to be used in the research of diseases caused by MBLs-related drug-resistant bacterial infections[1].
Product Specifications
CAS Number
[112243-88-6]
Product Name Alternative
Epi-D-SQ 14225
UNSPSC
12352005
Target
Beta-lactamase
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Smiles
SC[C@H](C)C(N1[C@H](CCC1)C(O)=O)=O
Molecular Formula
C9H15NO3S
Molecular Weight
217.29
References & Citations
[1]Brem J, et al. Structural Basis of Metallo-β-Lactamase Inhibition by Captopril Stereoisomers. Antimicrob Agents Chemother. 2015 Oct 19;60 (1) :142-50.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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