E3 ligase Ligand 64

E3 ligase Ligand 64 is a ligand for E3 ligase, used for the synthesis of RP03707 (HY-176134) [1].

Product Specifications

CAS Number

[2760850-50-6]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Ligands for E3 Ligase

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Purity

99.52

Smiles

O=C1NC(CCN1C2=NN(C)C3=C2C=C(F)C(Br)=C3)=O

Molecular Formula

C12H10BrFN4O2

Molecular Weight

341.14

Precautions

H302, H315, H319, H335

References & Citations

[1]Ji X, et al. Discovery and Characterization of RP03707: A Highly Potent and Selective KRASG12D PROTAC. J Med Chem. 2025 May 8.|[2]Ji X, et al. Discovery and Characterization of RP03707: A Highly Potent and Selective KRASG12D PROTAC. J Med Chem. 2025 May 8.