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ARS-1620 intermediate

ARS-1620 intermediate is an intermediate in the synthesis of a K-RasG12C inhibitor ARS1620 (HY-U00418) [1].

Product Specifications

CAS Number

[1698027-20-1]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Drug Intermediate

Related Pathways

Others

Field of Research

Others

Smiles

ClC1=C(Br)C(F)=C(N=CN=C2N3CCN(C(OC(C)(C)C)=O)CC3)C2=C1

Molecular Formula

C17H19BrClFN4O2

Molecular Weight

445.71

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Janes, M. R., et al., (2018) . Targeting KRAS Mutant Cancers with a Covalent G12C-Specific Inhibitor. Cell, 172 (3), 578–589.e17.

Shipping Conditions

Room temperature

Scientific Category

Reference compound2

Clinical Information

No Development Reported

Curated Selection

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