IDX-320

IDX-320 is a Pipecolic acid (HY-Y0669) derivative. IDX-320 inhibits NS3/4a proteases across genotypes 1a, 1b, 2a, and 4a with an IC50 0.8-1.9 nM. IDX-320 can be used in the research of HCV infection[1].

Product Specifications

CAS Number

[1251165-81-7]

UNSPSC

12352005

Target

Drug Derivative; HCV Protease

Related Pathways

Anti-infection; Metabolic Enzyme/Protease; Others

Field of Research

Infection

Smiles

O=C(NS(=O)(C1(CC1)C)=O)[C@]23NC([C@@](C[C@@H](OC4=CC(C5=NC(C(F)(F)F)=CS5)=NC6=C(C)C(OC)=CC=C46)CC7)([H])N7C(N(C)CCCC/C=C\[C@]2([H])C3)=O)=O

Molecular Formula

C37H43F3N6O7S2

Molecular Weight

804.90

References & Citations

[1]Liverton N J. Evolution of HCV NS3/4a Protease Inhibitors[M]//HCV: The Journey from Discovery to a Cure: Volume I. Cham: Springer International Publishing, 2019: 231-259.