CP-464709

CP-464709 is a Ghrelin receptor agonist that can penetrate the blood-brain barrier. CP-464709 causes an increase in blood pressure by activating pre sympathetic neurons in the spinal cord. CP-464709 causes biphasic blood pressure response when administered intravenously, while intrathecal administration only causes pressor. CP-464709 can be used for research on cardiovascular conditions[1].

Product Specifications

CAS Number

[193272-70-7]

UNSPSC

12352005

Target

GHSR

Related Pathways

GPCR/G Protein

Field of Research

Cardiovascular Disease

Smiles

CC(C)(N)C(N[C@H](COCC1=CC=C(F)C=C1F)C(N(C[C@]23CC4=NC=CC=C4)CCC2=NN(CC(F)(F)F)C3=O)=O)=O

Molecular Formula

C28H31F5N6O4

Molecular Weight

610.58

References & Citations

[1]Ferens DM, et al. Functional and in situ hybridization evidence that preganglionic sympathetic vasoconstrictor neurons express ghrelin receptors. Neuroscience. 2010 Mar 17;166 (2) :671-9.