2-NAP
2-NAP is a major metabolite of polycyclic aromatic hydrocarbons (PAHs) . 2-NAP induces oxidative stress and inflammatory responses, impairs enamel formation, and disrupts oral microbiome balance, increasing the risk of early childhood caries (ECC) . 2-NAP is promising for research of development-related diseases such as childhood caries[1].
Product Specifications
CAS Number
[141577-40-4]
UNSPSC
12352005
Target
Drug Metabolite
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Smiles
O=C(O)C[C@H](NS(=O)(C1=CC=C2C=CC=CC2=C1)=O)C(NCCC3=CC=CC=C3)=O
Molecular Formula
C22H22N2O5S
Molecular Weight
426.49
References & Citations
[1]Patil SS, et al. Association of prenatal and early-life polycyclic aromatic hydrocarbons exposure with dental caries in childhood. Environ Res. 2025 Oct 1;282:122021.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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