Minopafant

Minopafant (E 5880) is a PAF receptor antagonist. Minopafant can be used in studies of cerebral vasospasm following subarachnoid hemorrhage[1][2].

Product Specifications

CAS Number

[128420-61-1]

Product Name Alternative

E 5880

UNSPSC

12352005

Target

Platelet-activating Factor Receptor (PAFR)

Related Pathways

GPCR/G Protein

Field of Research

Neurological Disease; Cardiovascular Disease

Smiles

O=C(C1=C(C=CC=C1)OC)N(C(OC[C@H](OC)COC(N2CCC(CC2)OC(NCCCCCCCCCCCCCCCCCC)=O)=O)=O)CC3=CC=CC=[N+]3CC.[Cl-]

Molecular Formula

C46H73ClN4O9

Molecular Weight

861.55

References & Citations

[1]Hirashima Y, et al. Prevention of cerebrovasospasm following subarachnoid hemorrhage in rabbits by the platelet-activating factor antagonist, E5880[J]. Journal of neurosurgery, 1996, 84 (5) : 826-830.|[2]Hirashima Y, et al. Effect of a platelet-activating factor receptor antagonist, E5880, on cerebral vasospasm after aneurysmal subarachnoid hemorrhage--open clinical trial to investigate efficacy and safety. Neurol Med Chir (Tokyo) . 2001 Apr;41 (4) :165-75; discussion 175-6.