KW-3407
KW-3407 is an antiarrhythmic agent. KW-3407 can inhibit two-stage (24 and 48 h) coronary ligation-, digitalis- and adrenaline-induced spontaneously occurring arrhythmias with IC50 values of 18.1, 14.4, 18.3 and 21.4 μg/mL. KW-3407 can decrease the sinoatrial rate and contractile force, and increase the coronary blood flow and AV conduction times[1].
Product Specifications
CAS Number
[115750-37-3]
UNSPSC
12352100
Target
Others
Related Pathways
Others
Field of Research
Cardiovascular Disease
Smiles
CCN(CC)CCNC1C2=CC(OC)=CC=C2OCC3=NC=CC=C31.O=C(O)/C=C/C(O)=O.[3/2]
Molecular Formula
C20H27N3O2.3/2C4H4O4
Molecular Weight
515.56
References & Citations
[1]Wu Z, et al. [Effects of a new antiarrhythmic drug, KW-3407, on canine ventricular arrhythmia models]. Nihon Yakurigaku Zasshi. 1992 Aug;100 (2) :117-26. Japanese.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
