HAT-IN-10
HAT-IN-10 (Compound 12a) is an anti-human African trypanosomiasis (HAT) agent, with an EC50 value of 0.23 μM for T. brucei. HAT-IN-10 can be used for research on HAT[1].
Product Specifications
CAS Number
[2998560-77-1]
UNSPSC
12352005
Target
Paraptosis
Related Pathways
Apoptosis
Field of Research
Infection
Smiles
CN1C=C(C2=CC=C3C(C4=C(N3CCNC(C)C)C=CC(C5=CN(C)N=C5)=C4)=C2)C=N1
Molecular Formula
C25H28N6
Molecular Weight
412.53
References & Citations
[1]Singh B, et al. Chemical Optimization of CBL0137 for Human African Trypanosomiasis Lead Drug Discovery. J Med Chem. 2023 Feb 9;66 (3) :1972-1989.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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