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STING agonist-49

STING agonist-49 (Compound 1) is a STING agonist and can be used as a payload for ADCs. STING agonist-49 can be applied in lung cancer research[1].

Product Specifications

CAS Number

[2138299-66-6]

UNSPSC

12352005

Target

ADC Payload; STING

Related Pathways

Antibody-drug Conjugate/ADC Related; Immunology/Inflammation

Field of Research

Cancer

Smiles

O=C(C1=CC(C)=NN1CC)NC2=NC3=CC(C(N)=O)=CC(OC)=C3N2C/C=C/CN4C(NC(C5=CC(C)=NN5CC)=O)=NC6=C4C(OCCCNC)=CC(C(N)=O)=C6

Molecular Formula

C39H47N13O6

Molecular Weight

793.87

References & Citations

[1]Gruber DR, et al. Targeted delivery of a potent STING agonist payload via an antibody drug conjugate drives robust antitumor activity in preclinical models. Mol Cancer Ther. 2025 Oct 29.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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